4/4/2023 0 Comments Gantz chapter 129 indocin![]() ![]() The repeated course of ibuprofen for the treatment of hsPDA can be reduced. ![]() The results of the study indicated that prophylactic paracetamol use in ELBW infants decreases the likelihood of hsPDA. According to the results of the study, the male gender is 6.6, and the paracetamol use is 5.5 times more likely to suffer from ROP. Secondary outcomes were the other perinatal morbidities. Additionally, the repeated course of ibuprofen was significantly lower in the PPG (p=0.025). At the time of the evaluation by echo, hsPDA, and the diameter of the ductus higher than 1 mm were found significantly lower in the PPG (p=0.004 and p=0.013). Primary outcome measures were ductal closure, ductal diameter, grade 3–4 IVH, and repeated ibuprofen need for the treatment of hsPDA. There were 35 subjects in the prophylactic paracetamol group (PPG), and 40 in the control group. Prophylactic paracetamol as the experimental group and none-prophylaxis group as the control group were compared in the study. This study aims to evaluate the effects of prophylactic intravenous paracetamol on the hemodynamically significant patent ductus arteriosus (hsPDA).Ī total of 75 infants of <28 week-gestational age were enrolled into the study which was retrospective. ![]() Hemodynamic instability caused by PDA is associated with important morbidities. Patency of ductus arteriosus (PDA) is a very common problem among extremely low birth weight infants (ELBW). ![]()
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